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Hypomyelination and increased activity of voltage-gated K(+) channels in mice lacking protein tyrosine phosphatase ε

Protein tyrosine phosphatase epsilon (PTPε) is strongly expressed in the nervous system; however, little is known about its physiological role. We report that mice lacking PTPε exhibit hypomyelination of sciatic nerve axons at an early post-natal age. This occurs together with increased activity of...

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Detalhes bibliográficos
Main Authors: Peretz, A., Gil-Henn, H., Sobko, A., Shinder, V., Attali, B., Elson, A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC306594/
https://ncbi.nlm.nih.gov/pubmed/10921884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.15.4036
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