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B Lymphocytes Are Resistant to Death Receptor 5-induced Apoptosis

Death Receptor 5 (DR5) induces apoptosis in various types of cells and is a potential therapeutic target. We have investigated whether targeting DR5 could be used to eliminate pathogenic B lymphocytes from systemic lupus erythematosus (SLE) patients. We examined DR5 expression and function on B lymp...

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Detalhes bibliográficos
Main Authors: Crowder, Roslyn N., Zhao, Hong, Chatham, W. Winn, Zhou, Tong, Carter, Robert H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3065542/
https://ncbi.nlm.nih.gov/pubmed/21276756
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2010.12.006
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