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Autophagy induces apoptosis and death of T lymphocytes in the spleen of pigs infected with CSFV

Lymphocyte depletion and immunosuppression are typical clinical characteristics of pigs infected with classical swine fever virus (CSFV). The apoptosis of virus-infected and bystander cells plays a role in the immunopathology of classical swine fever (CSF). Here, we offer the first evidence that aut...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Gou, Hongchao, Zhao, Mingqiu, Fan, Shuangqi, Yuan, Jin, Liao, Jiedan, He, Wencheng, Xu, Hailuan, Chen, Jinding
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5648758/
https://ncbi.nlm.nih.gov/pubmed/29051589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-14082-9
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