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Whole body hypothermia broadens the therapeutic window of intranasally administered IGF-1 in a neonatal rat model of cerebral hypoxia-ischemia

To investigate whether whole body hypothermia after neonatal cerebral hypoxia-ischemia (HI) could broaden the therapeutic window of intranasal treatment of IGF-1 (iN-IGF-1), postnatal day 7 rat pups were subjected to right common carotid artery ligation, followed by 8% oxygen inhalation for 2 h. Aft...

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Autores principales: Lin, Shuying, Rhodes, Philip G., Cai, Zhengwei
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3065539/
https://ncbi.nlm.nih.gov/pubmed/21316352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2011.02.013
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