Enhanced Transduction and Replication of RGD-Fiber Modified Adenovirus in Primary T Cells

BACKGROUND: Adenoviruses are often used as vehicles to mediate gene delivery for therapeutic purposes, but their research scope in hematological cells remains limited due to a narrow choice of host cells that express the adenoviral receptor (CAR). T cells, which are attractive targets for gene thera...

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Main Authors: Sengupta, Sadhak, Ulasov, Ilya V., Thaci, Bart, Ahmed, Atique U., Lesniak, Maciej S.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3065494/
https://ncbi.nlm.nih.gov/pubmed/21464908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018091
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