Bone Marrow Mesenchymal Stem Cells Loaded With an Oncolytic Adenovirus Suppress the Anti-adenoviral Immune Response in the Cotton Rat Model

Oncolytic adenoviral virotherapy is an attractive treatment modality for cancer. However, following intratumoral injections, oncolytic viruses fail to efficiently migrate away from the injection site and are rapidly cleared by the immune system. We have previously demonstrated enhanced viral deliver...

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Detalhes bibliográficos
Main Authors: Ahmed, Atique U, Rolle, Cleo E, Tyler, Matthew A, Han, Yu, Sengupta, Sadhak, Wainwright, Derek A, Balyasnikova, Irina V, Ulasov, Ilya V, Lesniak, Maciej S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951553/
https://ncbi.nlm.nih.gov/pubmed/20588259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.131
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