Bone Marrow Mesenchymal Stem Cells Loaded With an Oncolytic Adenovirus Suppress the Anti-adenoviral Immune Response in the Cotton Rat Model

Oncolytic adenoviral virotherapy is an attractive treatment modality for cancer. However, following intratumoral injections, oncolytic viruses fail to efficiently migrate away from the injection site and are rapidly cleared by the immune system. We have previously demonstrated enhanced viral deliver...

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Autors principals: Ahmed, Atique U, Rolle, Cleo E, Tyler, Matthew A, Han, Yu, Sengupta, Sadhak, Wainwright, Derek A, Balyasnikova, Irina V, Ulasov, Ilya V, Lesniak, Maciej S
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2010
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951553/
https://ncbi.nlm.nih.gov/pubmed/20588259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.131
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