Bone Marrow Mesenchymal Stem Cells Loaded With an Oncolytic Adenovirus Suppress the Anti-adenoviral Immune Response in the Cotton Rat Model

Oncolytic adenoviral virotherapy is an attractive treatment modality for cancer. However, following intratumoral injections, oncolytic viruses fail to efficiently migrate away from the injection site and are rapidly cleared by the immune system. We have previously demonstrated enhanced viral deliver...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Ahmed, Atique U, Rolle, Cleo E, Tyler, Matthew A, Han, Yu, Sengupta, Sadhak, Wainwright, Derek A, Balyasnikova, Irina V, Ulasov, Ilya V, Lesniak, Maciej S
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2010
Sujets:
Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2951553/
https://ncbi.nlm.nih.gov/pubmed/20588259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.131
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