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Mitochondrial Structure and Function Are Disrupted by Standard Isolation Methods

Mitochondria regulate critical components of cellular function via ATP production, reactive oxygen species production, Ca(2+) handling and apoptotic signaling. Two classical methods exist to study mitochondrial function of skeletal muscles: isolated mitochondria and permeabilized myofibers. Whereas...

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Detalhes bibliográficos
Main Authors: Picard, Martin, Taivassalo, Tanja, Ritchie, Darmyn, Wright, Kathryn J., Thomas, Melissa M., Romestaing, Caroline, Hepple, Russell T.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3065478/
https://ncbi.nlm.nih.gov/pubmed/21512578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018317
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