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Advanced Computational Biology Methods Identify Molecular Switches for Malignancy in an EGF Mouse Model of Liver Cancer

The molecular causes by which the epidermal growth factor receptor tyrosine kinase induces malignant transformation are largely unknown. To better understand EGFs' transforming capacity whole genome scans were applied to a transgenic mouse model of liver cancer and subjected to advanced methods...

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Detalhes bibliográficos
Main Authors: Stegmaier, Philip, Voss, Nico, Meier, Tatiana, Kel, Alexander, Wingender, Edgar, Borlak, Juergen
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3065454/
https://ncbi.nlm.nih.gov/pubmed/21464922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017738
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