Extensive complement-dependent enhancement of HIV-1 by autologous non-neutralising antibodies at early stages of infection

BACKGROUND: Non-neutralising antibodies to the envelope glycoprotein are elicited during acute HIV-1 infection and are abundant throughout the course of disease progression. Although these antibodies appear to have negligible effects on HIV-1 infection when assayed in standard neutralisation assays,...

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Main Authors: Willey, Suzanne, Aasa-Chapman, Marlén MI, O'Farrell, Stephen, Pellegrino, Pierre, Williams, Ian, Weiss, Robin A, Neil, Stuart JD
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2011
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3065417/
https://ncbi.nlm.nih.gov/pubmed/21401915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-8-16
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