Neutrophil functions and autoimmune arthritis in the absence of p190RhoGAP: Generation and analysis of a novel null mutation in mice

β(2)-integrins of neutrophils play a critical role in innate immune defense but they also participate in tissue destruction during autoimmune inflammation. p190RhoGAP, a regulator of Rho-family small GTPases, is required for integrin signal transduction in fibroblasts. Prior studies have also sugges...

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Detaylı Bibliyografya
Asıl Yazarlar: Németh, Tamás, Futosi, Krisztina, Hably, Csilla, Brouns, Madeleine R., Jakob, Sascha M., Kovács, Miklós, Kertész, Zsuzsanna, Walzog, Barbara, Settleman, Jeffrey, Mócsai, Attila
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064944/
https://ncbi.nlm.nih.gov/pubmed/20675588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0904163
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