A multivalent DNA aptamer specific for the B-cell receptor on human lymphoma and leukemia

Long-term survival still eludes most patients with leukemia and non-Hodgkin’s lymphoma. No approved therapies target the hallmark of the B cell, its mIgM, also known as the B-cell receptor (BCR). Aptamers are small oligonucleotides that can specifically bind to a wide range of target molecules and o...

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Hlavní autoři: Mallikaratchy, Prabodhika R., Ruggiero, Alessandro, Gardner, Jeffrey R., Kuryavyi, Vitaly, Maguire, William F., Heaney, Mark L., McDevitt, Michael R., Patel, Dinshaw J., Scheinberg, David A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2011
Témata:
Synthetic Biology and Chemistry
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064813/
https://ncbi.nlm.nih.gov/pubmed/21030439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq996
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