Intralymphatic immunization enhances DNA vaccination

Although DNA vaccines have been shown to elicit potent immune responses in animal models, initial clinical trials in humans have been disappointing, highlighting a need to optimize their immunogenicity. Naked DNA vaccines are usually administered either i.m. or intradermally. The current study shows...

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Main Authors: Maloy, Kevin J., Erdmann, Iris, Basch, Veronique, Sierro, Sophie, Kramps, Thomas A., Zinkernagel, Rolf M., Oehen, Stefan, Kündig, Thomas M.
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences 2001
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC30648/
https://ncbi.nlm.nih.gov/pubmed/11248073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.051630798
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