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Pseudouridine at position 55 in tRNA controls the contents of other modified nucleotides for low-temperature adaptation in the extreme-thermophilic eubacterium Thermus thermophilus
Pseudouridine at position 55 (Ψ55) in eubacterial tRNA is produced by TruB. To clarify the role of the Ψ55 modification, we constructed a truB gene disruptant (ΔtruB) strain of Thermus thermophilus which is an extreme-thermophilic eubacterium. Unexpectedly, the ΔtruB strain exhibited severe growth r...
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Main Authors: | , , , , , , , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
Oxford University Press
2011
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3064792/ https://ncbi.nlm.nih.gov/pubmed/21097467 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq1180 |
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