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Pseudouridine at position 55 in tRNA controls the contents of other modified nucleotides for low-temperature adaptation in the extreme-thermophilic eubacterium Thermus thermophilus

Pseudouridine at position 55 (Ψ55) in eubacterial tRNA is produced by TruB. To clarify the role of the Ψ55 modification, we constructed a truB gene disruptant (ΔtruB) strain of Thermus thermophilus which is an extreme-thermophilic eubacterium. Unexpectedly, the ΔtruB strain exhibited severe growth r...

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Main Authors: Ishida, Kazuo, Kunibayashi, Takashi, Tomikawa, Chie, Ochi, Anna, Kanai, Tamotsu, Hirata, Akira, Iwashita, Chikako, Hori, Hiroyuki
格式: Artigo
語言:Inglês
出版: Oxford University Press 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064792/
https://ncbi.nlm.nih.gov/pubmed/21097467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq1180
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