A methodology for radiolabeling of the endocannabinoid 2-arachidonoylglycerol (2-AG)

The metabolic intermediate and endocannabinoid signaling lipid 2-arachidonoylglycerol (2-AG) has not been readily labeled, primarily due to its instability towards rearrangement. We now detail a synthetic method that easily gives tritiated 2-AG from [5,6,8,9,11,12,14,15-(3)H(N)]arachidonic acid in t...

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Autori principali: Duclos, Richard I., Johnston, Meghan, Vadivel, Subramanian K., Makriyannis, Alexandros, Glaser, Sherrye T., Gatley, S. John
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064716/
https://ncbi.nlm.nih.gov/pubmed/21370840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo102277q
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