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Enhanced anti-Diastereo- and Enantioselectivity in Alcohol Mediated Carbonyl Crotylation Using an Isolable Single Component Iridium Catalyst

[Image: see text] The cyclometallated iridium complex (S)-I derived from [Ir(cod)Cl](2), 4-cyano-3-nitrobenzoic acid, allyl acetate and (S)-SEGPHOS is conveniently isolated by precipitation or through conventional silica gel flash chromatography. This single component precatalyst allows alcohol medi...

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Main Authors: Gao, Xin, Townsend, Ian A., Krische, Michael J.
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064714/
https://ncbi.nlm.nih.gov/pubmed/21375283
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo200068q
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