Ligand-independent assembly of recombinant human CD1 by using oxidative refolding chromatography

CD1 is an MHC class I-like antigen-presenting molecule consisting of a heavy chain and β(2)-microglobulin light chain. The in vitro refolding of synthetic MHC class I molecules has always required the presence of ligand. We report here the use of a folding method using an immobilized chaperone fragm...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Altamirano, Myriam M., Woolfson, Adrian, Donda, Alena, Shamshiev, Abdijapar, Briseño-Roa, Luis, Foster, Nicholas W., Veprintsev, Dmitry B., De Libero, Gennaro, Fersht, Alan R., Milstein, César
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2001
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC30646/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11248071/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.041596598
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