Altered Gene Expression in Pulmonary Tissue of Tryptophan Hydroxylase-1 Knockout Mice: Implications for Pulmonary Arterial Hypertension

The use of fenfluramines can increase the risk of developing pulmonary arterial hypertension (PAH) in humans, but the mechanisms responsible are unresolved. A recent study reported that female mice lacking the gene for tryptophan hydroxylase-1 (Tph1(−/−) mice) were protected from PAH caused by chron...

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書誌詳細
主要な著者: Rothman, Richard B., Cadet, Jean L., Dersch, Christina M., McCoy, Michael T., Lehrmann, Elin, Becker, Kevin G., Bader, Michael, Alenina, Natalia, Baumann, Michael H.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2011
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064573/
https://ncbi.nlm.nih.gov/pubmed/21464983
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017735
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