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Peptide ligands that use a novel binding site to target both TGF-β receptors

The transforming growth factor β (TGF-β) signaling pathway plays myriad roles in development and disease. TGF-β isoforms initiate signaling by organizing their cell surface receptors TβRI and TβRII. Exploration and exploitation of the versatility of TGF-β signaling requires enhanced understanding of...

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Detalhes bibliográficos
Main Authors: Li, Lingyin, Orner, Brendan P., Huang, Tao, Hinck, Andrew P., Kiessling, Laura L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064480/
https://ncbi.nlm.nih.gov/pubmed/20890540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c0mb00115e
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