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A Comprehensive Examination of the Contributions to Binding Entropy of Protein-Ligand Complexes

The process of ligand binding is very complex due to the intricacy of the interrelated processes that are difficult to predict and quantify. One of the most important requirements in computer-aided drug design is the ability to reliably evaluate the binding free energies. However, deeper understandi...

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Hlavní autoři: Singh, Nidhi, Warshel, Arieh
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064472/
https://ncbi.nlm.nih.gov/pubmed/20186973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22689
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