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A Comprehensive Examination of the Contributions to Binding Entropy of Protein-Ligand Complexes

The process of ligand binding is very complex due to the intricacy of the interrelated processes that are difficult to predict and quantify. One of the most important requirements in computer-aided drug design is the ability to reliably evaluate the binding free energies. However, deeper understandi...

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Bibliografiske detaljer
Main Authors: Singh, Nidhi, Warshel, Arieh
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064472/
https://ncbi.nlm.nih.gov/pubmed/20186973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22689
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