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G-protein coupled receptor kinase 5 mediates Lipopolysaccharide-induced NFκB activation in primary macrophages and modulates inflammation in vivo in mice

G-protein coupled receptor kinase-5 (GRK5) is a serine/threonine kinase discovered for its role in the regulation of G-protein coupled receptor signaling. Recent studies have shown that GRK5 is also an important regulator of signaling pathways stimulated by non-GPCRs. This study was undertaken to de...

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Detalhes bibliográficos
Main Authors: Patial, Sonika, Shahi, Shipra, Saini, Yogesh, Lee, Taehyung, Packiriswamy, Nandakumar, Appledorn, Daniel M., LaPres, John J., Amalfitano, Andrea, Parameswaran, Narayanan
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064424/
https://ncbi.nlm.nih.gov/pubmed/20945396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.22460
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