Noncanonical Wnt signaling mediates androgen-dependent tumor growth in a mouse model of prostate cancer

Prostate cancer development is associated with hyperactive androgen signaling. However, the molecular link between androgen receptor (AR) function and humoral factors remains elusive. A prostate cancer mouse model was generated by selectively mutating the AR threonine 877 into alanine in prostatic e...

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Hauptverfasser: Takahashi, Sayuri, Watanabe, Tomoyuki, Okada, Maiko, Inoue, Kazuki, Ueda, Takashi, Takada, Ichiro, Watabe, Tetsuro, Yamamoto, Yoko, Fukuda, Toru, Nakamura, Takashi, Akimoto, Chihiro, Fujimura, Tetsuya, Hoshino, Maiko, Imai, Yuuki, Metzger, Daniel, Miyazono, Kohei, Minami, Yasuhiro, Chambon, Pierre, Kitamura, Tadaichi, Matsumoto, Takahiro, Kato, Shigeaki
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2011
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064378/
https://ncbi.nlm.nih.gov/pubmed/21383160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1014850108
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