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Axial Hox9 activity establishes the posterior field in the developing forelimb

Current models hold that the early limb field becomes polarized into anterior and posterior domains by the opposing activities of Hand2 and Gli3. This polarization is essential for the initiation of Shh expression in the posterior margin of the limb bud, but how this polarity is established is not c...

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Autori principali: Xu, Ben, Wellik, Deneen M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064354/
https://ncbi.nlm.nih.gov/pubmed/21383175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1018161108
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