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Hox5 interacts with Plzf to restrict Shh expression in the developing forelimb

To date, only the five most posterior groups of Hox genes, Hox9–Hox13, have demonstrated loss-of-function roles in limb patterning. Individual paralog groups control proximodistal patterning of the limb skeletal elements. Hox9 genes also initiate the onset of Hand2 expression in the posterior foreli...

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Autori principali: Xu, Ben, Hrycaj, Steven M., McIntyre, Daniel C., Baker, Nicholas C., Takeuchi, Jun K., Jeannotte, Lucie, Gaber, Zachary B., Novitch, Bennett G., Wellik, Deneen M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3845161/
https://ncbi.nlm.nih.gov/pubmed/24218595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1315075110
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