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Casein kinase II-mediated phosphorylation of general repressor Maf1 triggers RNA polymerase III activation
Maf1 protein is a global negative regulator of RNA polymerase (Pol) III transcription conserved from yeast to man. We report that phosphorylation of Maf1 by casein kinase II (CK2), a highly evolutionarily conserved eukaryotic kinase, is required for efficient Pol III transcription. Both recombinant...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
National Academy of Sciences
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3064340/ https://ncbi.nlm.nih.gov/pubmed/21383183 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1010010108 |
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