Effects of low-level α-myosin heavy chain expression on contractile kinetics in porcine myocardium

Myosin heavy chain (MHC) isoforms are principal determinants of work capacity in mammalian ventricular myocardium. The ventricles of large mammals including humans normally express ∼10% α-MHC on a predominantly β-MHC background, while in failing human ventricles α-MHC is virtually eliminated, sugges...

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Bibliografiset tiedot
Päätekijät: Locher, Matthew R., Razumova, Maria V., Stelzer, Julian E., Norman, Holly S., Moss, Richard L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Physiological Society 2011
Aiheet:
Muscle Mechanics and Ventricular Function
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064314/
https://ncbi.nlm.nih.gov/pubmed/21217059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00452.2010
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