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Determination of rate constants for turnover of myosin isoforms in rat myocardium: implications for in vivo contractile kinetics
The ventricles of small mammals express mostly α-myosin heavy chain (α-MHC), a fast isoform, whereas the ventricles of large mammals, including humans, express ∼10% α-MHC on a predominately β-MHC (slow isoform) background. In failing human ventricles, the amount of α-MHC is dramatically reduced, lea...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Physiological Society
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2711735/ https://ncbi.nlm.nih.gov/pubmed/19395549 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00922.2008 |
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