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Dual-specific Phosphatase-6 (Dusp6) and ERK Mediate AMPA Receptor-induced Oligodendrocyte Death

Oligodendrocytes, the myelinating cells of the CNS, are highly vulnerable to glutamate excitotoxicity, a mechanism involved in tissue damage in multiple sclerosis. Thus, understanding oligodendrocyte death at the molecular level is important to develop new therapeutic approaches to treat the disease...

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Detalles Bibliográficos
Main Authors: Domercq, Maria, Alberdi, Elena, Sánchez-Gómez, Maria Victoria, Ariz, Usue, Pérez-Samartín, Alberto, Matute, Carlos
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064233/
https://ncbi.nlm.nih.gov/pubmed/21300799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.153049
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