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Toward optimized carbohydrate-based anticancer vaccines: Epitope clustering, carrier structure, and adjuvant all influence antibody responses to Lewis(y) conjugates in mice

The feasibility of using carbohydrate-based vaccines for the immunotherapy of cancer is being actively explored at the present time. Although a number of clinical trials have already been conducted with glycoconjugate vaccines, the optimal design and composition of the vaccines has yet to be determi...

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Detalhes bibliográficos
Main Authors: Kudryashov, Valery, Glunz, Peter W., Williams, Lawrence J., Hintermann, Samuel, Danishefsky, Samuel J., Lloyd, Kenneth O.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC30642/
https://ncbi.nlm.nih.gov/pubmed/11248067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.051623598
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