Synthetic peptides representing T-cell epitopes act as carriers in pneumococcal polysaccharide conjugate vaccines.

Improvement of antibody responses to polysaccharides through their linkage to proteins is thought to be mediated by protein-specific T helper (Th) cells. To investigate whether the carrier protein of a conjugate could be substituted by a Th epitope, Streptococcus pneumoniae type 17F polysaccharide (...

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Detalhes bibliográficos
Main Authors: de Velasco, E A, Merkus, D, Anderton, S, Verheul, A F, Lizzio, E F, Van der Zee, R, Van Eden, W, Hoffman, T, Verhoef, J, Snippe, H
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC173096/
https://ncbi.nlm.nih.gov/pubmed/7532630
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