Synthetic peptides representing T-cell epitopes act as carriers in pneumococcal polysaccharide conjugate vaccines.

Improvement of antibody responses to polysaccharides through their linkage to proteins is thought to be mediated by protein-specific T helper (Th) cells. To investigate whether the carrier protein of a conjugate could be substituted by a Th epitope, Streptococcus pneumoniae type 17F polysaccharide (...

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Detalles Bibliográficos

Publicado en:	Infect Immun
Autores principales:	de Velasco, E A, Merkus, D, Anderton, S, Verheul, A F, Lizzio, E F, Van der Zee, R, Van Eden, W, Hoffman, T, Verhoef, J, Snippe, H
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 1995
Materias:	Research Article
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC173096/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7532630/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.63.3.961-968.1995
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