Allele-specific Effects of Thoracic Aortic Aneurysm and Dissection α-Smooth Muscle Actin Mutations on Actin Function

Twenty-two missense mutations in ACTA2, which encodes α-smooth muscle actin, have been identified to cause thoracic aortic aneurysm and dissection. Limited access to diseased tissue, the presence of multiple unresolvable actin isoforms in the cell, and lack of an animal model have prevented analysis...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Bergeron, Sarah E., Wedemeyer, Elesa W., Lee, Rose, Wen, Kuo-Kuang, McKane, Melissa, Pierick, Alyson R., Berger, Anthony P., Rubenstein, Peter A., Bartlett, Heather L.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2011
Fag:
Protein Structure and Folding
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064192/
https://ncbi.nlm.nih.gov/pubmed/21288906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.203174
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker