Protein Kinase D Negatively Regulates Hepatitis C Virus Secretion through Phosphorylation of Oxysterol-binding Protein and Ceramide Transfer Protein

Hepatitis C virus (HCV) RNA replicates its genome on specialized endoplasmic reticulum modified membranes termed membranous web and utilizes lipid droplets for initiating the viral nucleocapsid assembly. HCV maturation and/or the egress pathway requires host sphingolipid synthesis, which occur in th...

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Bibliographic Details
Main Authors: Amako, Yutaka, Syed, Gulam H., Siddiqui, Aleem
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2011
Subjects:
Microbiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064182/
https://ncbi.nlm.nih.gov/pubmed/21285358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.182097
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