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TonEBP stimulates multiple cellular pathways for adaptation to hypertonic stress: organic osmolyte-dependent and -independent pathways

TonEBP (tonicity-responsive enhancer binding protein) is a transcription factor that promotes cellular accumulation of organic osmolytes in the hypertonic renal medulla by stimulating expression of its target genes. Genetically modified animals with deficient TonEBP activity in the kidney suffer fro...

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Autors principals: Lee, Sang Do, Choi, Soo Youn, Lim, Sun Woo, Lamitina, S. Todd, Ho, Steffan N., Go, William Y., Kwon, H. Moo
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064130/
https://ncbi.nlm.nih.gov/pubmed/21209002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00227.2010
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