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Hyperuricemia as a Mediator of the Proinflammatory Endocrine Imbalance in the Adipose Tissue in a Murine Model of the Metabolic Syndrome

OBJECTIVE: Hyperuricemia is strongly associated with obesity and metabolic syndrome and can predict visceral obesity and insulin resistance. Previously, we showed that soluble uric acid directly stimulated the redox-dependent proinflammatory signaling in adipocytes. In this study we demonstrate the...

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Detalhes bibliográficos
Main Authors: Baldwin, William, McRae, Steven, Marek, George, Wymer, David, Pannu, Varinderpal, Baylis, Chris, Johnson, Richard J., Sautin, Yuri Y.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064099/
https://ncbi.nlm.nih.gov/pubmed/21346177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-0916
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