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Role of oxidative stress in the renal abnormalities induced by experimental hyperuricemia

Endothelial dysfunction is a characteristic feature during the renal damage induced by mild hyperuricemia. The mechanism by which uric acid reduces the bioavailability of intrarenal nitric oxide is not known. We tested the hypothesis that oxidative stress might contribute to the endothelial dysfunct...

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Detalhes bibliográficos
Main Authors: Sánchez-Lozada, Laura G., Soto, Virgilia, Tapia, Edilia, Avila-Casado, Carmen, Sautin, Yuri Y., Nakagawa, Takahiko, Franco, Martha, Rodríguez-Iturbe, Bernardo, Johnson, Richard J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2576157/
https://ncbi.nlm.nih.gov/pubmed/18701632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00104.2008
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