Treatment with pyrrolidine dithiocarbamate improves proteinuria, oxidative stress, and glomerular hypertension in overload proteinuria

We evaluated whether the blockade of the proinflammatory transcription factor NF-κB would modify the oxidative stress, inflammation, and structural and hemodynamic alterations found in the kidney as a result of massive proteinuria. Twenty male Sprague-Dawley rats were injected with 2 g of BSA intrap...

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Main Authors: Tapia, Edilia, Sánchez-González, Dolores J., Medina-Campos, Omar N., Soto, Virgilia, Ávila-Casado, Carmen, Martínez-Martínez, Claudia M., Johnson, Richard J., Rodríguez-Iturbe, Bernardo, Pedraza-Chaverrí, José, Franco, Martha, Sánchez-Lozada, Laura G.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2008
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2584905/
https://ncbi.nlm.nih.gov/pubmed/18753301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.90201.2008
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