Hematopoietic Cell–Restricted Deletion of CD36 Reduces High-Fat Diet–Induced Macrophage Infiltration and Improves Insulin Signaling in Adipose Tissue

OBJECTIVE: The fatty acid translocase and scavenger receptor CD36 is important in the recognition and uptake of lipids. Accordingly, we hypothesized that it plays a role in saturated fatty acid–induced macrophage lipid accumulation and proinflammatory activation. RESEARCH DESIGN AND METHODS: In vitr...

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Detalhes bibliográficos
Main Authors: Nicholls, Hayley T., Kowalski, Greg, Kennedy, David J., Risis, Steve, Zaffino, Lee A., Watson, Nadine, Kanellakis, Peter, Watt, Matthew J., Bobik, Alex, Bonen, Arend, Febbraio, Maria, Lancaster, Graeme I., Febbraio, Mark A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2011
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064084/
https://ncbi.nlm.nih.gov/pubmed/21378177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-1353
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