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Endoplasmic Reticulum Stress Promotes LIPIN2-Dependent Hepatic Insulin Resistance
OBJECTIVE: Diet-induced obesity (DIO) is linked to peripheral insulin resistance—a major predicament in type 2 diabetes. This study aims to identify the molecular mechanism by which DIO-triggered endoplasmic reticulum (ER) stress promotes hepatic insulin resistance in mouse models. RESEARCH DESIGN A...
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| Hauptverfasser: | , , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Diabetes Association
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3064081/ https://ncbi.nlm.nih.gov/pubmed/21357464 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-1046 |
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