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Puromycin aminonucleoside triggers apoptosis in podocytes by inducing endoplasmic reticulum stress
BACKGROUND: Puromycin aminonucleoside (PAN) is a known podocytotoxin. PAN-induced nephrosis is a widely used animal model for studying human idiopathic nephrotic syndrome. Abnormal protein accumulation associated with podocyte-specific endoplasmic reticulum (ER) stress damages cells structurally and...
Shranjeno v:
| izdano v: | Kidney Res Clin Pract |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Korean Society of Nephrology
2018
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6147198/ https://ncbi.nlm.nih.gov/pubmed/30254845 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.23876/j.krcp.2018.37.3.210 |
| Oznake: |
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