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Role of integrins in angiotensin II-induced proliferation of vascular smooth muscle cells

Angiotensin II (AII) binds to G protein-coupled receptor AT(1) and stimulates extracellular signal-regulated kinase (ERK), leading to vascular smooth muscle cells (VSMC) proliferation. Proliferation of mammalian cells is tightly regulated by adhesion to the extracellular matrix, which occurs via int...

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Détails bibliographiques
Auteurs principaux: Bunni, Marlene A., Kramarenko, Inga I., Walker, Linda, Raymond, John R., Garnovskaya, Maria N.
Format: Artigo
Langue:Inglês
Publié: American Physiological Society 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3063971/
https://ncbi.nlm.nih.gov/pubmed/21148411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00179.2010
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