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Increased Presynaptic and Postsynaptic α(2)-Adrenoceptor Activity in the Spinal Dorsal Horn in Painful Diabetic Neuropathy

Diabetic neuropathy is a common cause of chronic pain that is not adequately relieved by conventional analgesics. The α(2)-adrenoceptors are involved in the regulation of glutamatergic input and nociceptive transmission in the spinal dorsal horn, but their functional changes in diabetic neuropathy a...

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Detalhes bibliográficos
Main Authors: Chen, Shao-Rui, Chen, Hong, Yuan, Wei-Xiu, Pan, Hui-Lin
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3063741/
https://ncbi.nlm.nih.gov/pubmed/21248068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.110.176586
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