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Increased Presynaptic and Postsynaptic α(2)-Adrenoceptor Activity in the Spinal Dorsal Horn in Painful Diabetic Neuropathy
Diabetic neuropathy is a common cause of chronic pain that is not adequately relieved by conventional analgesics. The α(2)-adrenoceptors are involved in the regulation of glutamatergic input and nociceptive transmission in the spinal dorsal horn, but their functional changes in diabetic neuropathy a...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The American Society for Pharmacology and Experimental Therapeutics
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3063741/ https://ncbi.nlm.nih.gov/pubmed/21248068 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.110.176586 |
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