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Effect of broad- and narrow-spectrum antimicrobials on Clostridium difficile and microbial diversity in a model of the distal colon

Vancomycin, metronidazole, and the bacteriocin lacticin 3147 are active against a wide range of bacterial species, including Clostridium difficile. We demonstrate that, in a human distal colon model, the addition of each of the three antimicrobials resulted in a significant decrease in numbers of C....

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Detalhes bibliográficos
Main Authors: Rea, Mary C., Dobson, Alleson, O'Sullivan, Orla, Crispie, Fiona, Fouhy, Fiona, Cotter, Paul D., Shanahan, Fergus, Kiely, Barry, Hill, Colin, Ross, R. Paul
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3063588/
https://ncbi.nlm.nih.gov/pubmed/20616009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1001224107
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