Human CD14(dim) Monocytes Patrol and Sense Nucleic Acids and Viruses via TLR7 and TLR8 Receptors

Monocytes are effectors of the inflammatory response to microbes. Human CD14(+) monocytes specialize in phagocytosis and production of reactive oxygen species and secrete inflammatory cytokines in response to a broad range of microbial cues. Here, we have characterized the functions of human monocyt...

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Main Authors: Cros, Jérôme, Cagnard, Nicolas, Woollard, Kevin, Patey, Natacha, Zhang, Shen-Ying, Senechal, Brigitte, Puel, Anne, Biswas, Subhra K., Moshous, Despina, Picard, Capucine, Jais, Jean-Philippe, D'Cruz, David, Casanova, Jean-Laurent, Trouillet, Céline, Geissmann, Fréderic
Format: Artigo
Sprog:Inglês
Udgivet: Cell Press 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3063338/
https://ncbi.nlm.nih.gov/pubmed/20832340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.immuni.2010.08.012
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