Normalization of Obesity-Associated Insulin Resistance through Immunotherapy: CD4+ T Cells Control Glucose Homeostasis

Progressive obesity and its associated metabolic syndromes represent a globally growing challenge, yet mechanistic understanding and current therapeutics are unsatisfactory. We discovered that CD4+ T-lymphocytes, resident in visceral adipose tissue (VAT), control insulin-resistance in diet-induced o...

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Bibliografiske detaljer
Main Authors: Winer, Shawn, Chan, Yin, Paltser, Geoffrey, Truong, Dorothy, Tsui, Hubert, Bahrami, Jasmine, Dorfman, Ruslan, Wang, Yongqian, Zielenski, Julian, Mastronardi, Fabrizio, Maezawa, Yuko, Drucker, Daniel, Engleman, Edgar, Winer, Daniel, Dosch, H.-Michael
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3063199/
https://ncbi.nlm.nih.gov/pubmed/19633657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2001
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