Human Primary Adipocytes Exhibit Immune Cell Function: Adipocytes Prime Inflammation Independent of Macrophages

BACKGROUND: Obesity promotes inflammation in adipose tissue (AT) and this is implicated in pathophysiological complications such as insulin resistance, type 2 diabetes and cardiovascular disease. Although based on the classical hypothesis, necrotic AT adipocytes (ATA) in obese state activate AT macr...

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Detalhes bibliográficos
Main Authors: Meijer, Kees, de Vries, Marcel, Al-Lahham, Saad, Bruinenberg, Marcel, Weening, Desirée, Dijkstra, Martijn, Kloosterhuis, Niels, van der Leij, Roelof Jan, van der Want, Han, Kroesen, Bart-Jan, Vonk, Roel, Rezaee, Farhad
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3063154/
https://ncbi.nlm.nih.gov/pubmed/21448265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017154
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