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PGL proteins self associate and bind RNPs to mediate germ granule assembly in C. elegans

Germ granules are germ lineage–specific ribonucleoprotein (RNP) complexes, but how they are assembled and specifically segregated to germ lineage cells remains unclear. Here, we show that the PGL proteins PGL-1 and PGL-3 serve as the scaffold for germ granule formation in Caenorhabditis elegans. Usi...

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Detalhes bibliográficos
Main Authors: Hanazawa, Momoyo, Yonetani, Masafumi, Sugimoto, Asako
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3063142/
https://ncbi.nlm.nih.gov/pubmed/21402787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201010106
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