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PGL proteins self associate and bind RNPs to mediate germ granule assembly in C. elegans
Germ granules are germ lineage–specific ribonucleoprotein (RNP) complexes, but how they are assembled and specifically segregated to germ lineage cells remains unclear. Here, we show that the PGL proteins PGL-1 and PGL-3 serve as the scaffold for germ granule formation in Caenorhabditis elegans. Usi...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
The Rockefeller University Press
2011
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3063142/ https://ncbi.nlm.nih.gov/pubmed/21402787 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201010106 |
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