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Adenine specific DNA chemical sequencing reaction.
Reaction of DNA with K2PdCl4 at pH 2.0 followed by a piperidine workup produces specific cleavage at adenine (A) residues. Product analysis revealed the K2PdCl4 reaction involves selective depurination at adenine, affording an excision reaction analogous to the other chemical DNA sequencing reaction...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
1987
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| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC306310/ https://ncbi.nlm.nih.gov/pubmed/3671067 |
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